Fatigue (feeling really tired) is one of the most common side effects of cancer treatment and ranks at the top of symptoms reported (alongside pain). Simple activities required of daily living can take longer, use up more energy, and feel debilitating. It’s important to talk with your health care team if you experience fatigue.

Causes of Fatigue

  • Cancer treatment. One of the most common causes of fatigue is chemotherapy—it can lower the number of red cells in your blood, which carry oxygen throughout your body and give you energy. Having fewer red blood cells means that you can get “out of breath” when you do something even mildly strenuous.
  • Cancer itself
  • Coping with cancer emotionally
  • Cancer pain
  • Anemia (low levels of red blood cells, the iron-containing cells that carry vital oxygen from the lungs to the muscles and other tissues in the body)

Keep a side effect journal. If you experience any treatment side effects, starting a health care journal can help. A health care journal or notebook helps you to keep all your health information in one place. If you are experiencing fatigue, it may be helpful to write down the following in your journal or notebook:

  • When you experience fatigue
  • How long the fatigue lasted
  • Your diet
  • Any activities you engaged in when you first felt fatigue

Have this journal with you any time to you talk to your health care team.

Questions to Ask Your Health Care Team

As with any side effect experienced during treatment, it’s important to talk to your health care team if you feel fatigue. Write down your questions and concerns about any side effects and treatment in your health care journal before your next medical appointment. In addition to bringing questions, if possible, bring someone with you to any appointment. Another set of ears can help reduce confusion. Here are questions that may want to ask your health care team:

  • What is the cause of my fatigue?
  • How long can I expect my fatigue to last?
  • What action should I take when I feel fatigue?
  • What exercises or foods do you recommend to improve my energy level?
  • Are there activities or foods I should avoid?

If you are experiencing fatigue, you should know that this is a symptom for which you can and should seek help. If your doctor doesn’t ask you about fatigue, be sure to bring it up. That’s the best way to find and treat the cause.

Treating Fatigue

To determine whether there is an unrelated physical cause (like anemia) to your fatigue, your doctor may order a blood test to find out if your red blood cell count is abnormally low. If you are anemic, there are treatment options available. Take only treatments prescribed by your doctor. Do not treat yourself with over-the-counter medicines for “iron-poor blood.” These medicines have not proven to be helpful.

There are some simple things you can do to help yourself when experiencing fatigue:

  • Take a 30-minute nap or breaks in a comfortable chair or bed.
  • Try simple exercises such as walking or yoga, which can help regain energy and clear the mind.
  • Try easier or shorter versions of the activities you enjoy.
  • Ask your family or friends to help when you feel too tired to do something yourself.
  • Pace yourself but try to stay active; conserve your energy for your priorities and find your own comfort level.

An Oncology Social Worker Can Help

Professional oncology social workers at CancerCare understand the complex issues that arise with a cancer diagnosis. Social workers can help you manage any emotional or practical concerns that may be causing symptoms and help you develop ways to cope. CancerCare’s professional oncology social workers help anyone affected by cancer, free of charge. To speak with a professional oncology social worker, call 800-813-HOPE (4673).

Edited by Laurie Feingold

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This fact sheet is supported by Bristol Meyers Squibb, Pharmacyclics LLC, an AbbVie Company and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC. and Takeda Oncology.

Last updated June 24, 2022

The information presented in this publication is provided for your general information only. It is not intended as medical advice and should not be relied upon as a substitute for consultations with qualified health professionals who are aware of your specific situation. We encourage you to take information and questions back to your individual health care provider as a way of creating a dialogue and partnership about your cancer and your treatment.

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